Rutgers-New York University Center for Asian Health Promotion and Equity Call for Pilot Proposals Request for Applications

Center:

Applications being accepted for one-year NIH/NIMHD-funded Pilot-Study
Awards up to $35,000 each
Intend to fund up to six awards in this cycle

Key dates

Deadline for Application Submission: January 17, 2023, by 11:50 PM EST
Earliest Anticipated Award Date: March 2023 (after NIH approval)

Overview and goals

Several chronic health diagnoses disproportionately impact US Asians, including cardiovascular disease, diabetes, and hypertension. Many Asian subgroups have a higher prevalence of cardiometabolic disease than non-Hispanic white counterparts. 1-6 However, health disparities are disguised due to aggregation of Asian racial category; thus, there is a call for research to use disaggregated data.2,7

The goal of our P50 CAHPE is to improve cardiometabolic and mental health-related research involving U.S. Asian adults. This will be accomplished through supporting both large-scale and small-scale projects on cardiometabolic and mental health among US Asians. Through these pilot projects, we aim to develop a pipeline of qualified researchers focused on Asian health disparities in cardiometabolic and mental health.

Pilot Project Awards will support collaborative projects conducting innovative research that focuses on the intersection of cardiometabolic disease and mental health among Asians (comparative research between U.S. Asian adults and other populations also qualify). This research can span the disciplines of basic science, population studies, or social science. Projects can focus on primary data collection or secondary data analyses. Projects that include a diverse sample of Asian ethnicities and include sub- group analysis to reflect the heterogeneity of U.S. Asian adults are encouraged. For more information about the Center for Asian Health Promotion and Equity (CAHPE, pronounced “cape”) and aims, please refer to our project description.

Pilot projects are expected to address determinants of health at two or more levels of influence (individual, interpersonal/organizations, community, societal; see NIMHD Research Framework for more information) that are relevant to cardiometabolic disease and mental health disparities among Asians in NJ/NY. All investigators will be strongly encouraged to use common data elements and measures that have been vetted through the NIH PhenX-Toolkit process, especially for social determinants of health. Please see the appendix for a list of common data elements in our Center.

Eligibility

All advanced post-doctoral fellows or early-stage investigators (at instructor, assistant, or associate professor level) who are not only interested in becoming an independent investigator, but also in pursuing research regarding health disparities among U.S. Asian adults are eligible to apply. Principal investigators who have previously received or who are current recipients of NIH R01-level or equivalent funding are not eligible for this funding mechanism. Minority scholars are encouraged to apply.

Applicants will be academic, clinical, or community-based researchers preferably based in the New York/New Jersey area.

Full application guideline

The application must include all sections outlined below.

Cover Page and Abstract 

On the cover page please include:

  1. The title of the project
  2. Names, faculty ranks, and institutions of PI and all other co-investigators/collaborators/mentorship team
  3. The PI’s contact information (phone number and email address). Additionally, provide an abstract description of the proposed research project in layman’s terms (250 words or fewer).

Research Proposal

The proposal should describe the research plan and should include:

  1. Specific aims
  2. Scientific significance and innovation
  3. Preliminary studies
  4. Research design and methods, including any analytic procedures
  5. Limitations
  6. Information on how the proposed project will lead to peer-reviewed funding
  7. Plans for the PI’s career development and mentorship
  8. The added value that the proposed research brings to the Rutgers-NYU CAHPE and the U.S. Asian adult population. This section is limited to 3 pages excluding figures, tables and references. Appendix material will not be accepted. Proposals should be submitted using 11-point Arial font and no less than 0.5” margins.

Biosketches

Current NIH Biosketches (this should include all other funding sources) is required for the PI. Biosketches should be submitted on the current NIH Biographical Sketch Format.

Budget

Requests NOT EXCEEDING the award amount should be submitted on the NIH budget form, and budget justifications should be submitted to match the budget form.

Outline major divisions of funds (personnel/effort support, equipment, supplies, other, etc.; and include adequate rationale in the budget justification). Funds should be used for research-related activities, excluding travel expenses for conferences. All budget estimates include direct costs only. Indirect costs are unallowable.

Please consult with the Office of Sponsor Program of your Institution to confirm what the grant submission requirements are.

Institutional matching funds are preferred, but not required, to cover additional effort or research related costs.

Human Subjects portion

The applicant will provide written study protocols that address risks and protections for human subjects in

accordance with NIH’s Instructions for Preparing the Human Subjects Section of the Research Plan and specific plans for data and safety monitoring if applicable.

If IRB approval is necessary for the proposed research, approval will be required prior to receiving funding (IRB approval is not needed for the pilot application review).

Letters of Support

It is required that your primary mentor provides a letter of support for your application to show his/her commitment to your proposed study.

In addition, if you are working with any community partners to recruit participants or collect data, please also include letter(s) of support from the relevant community partners.

Format

All items must be compiled and submitted as a single PDF file. Please number each page. All application submissions can be submitted by the investigator to our email [email protected] or through the Institution’s Office of Sponsor Program. All inquiries related to this request for proposals should also be directed via email to [email protected].

Application Deadline

January 17, 2023 by 11:59 PM EST

Pilot Proposal Review Criteria

Applications will be reviewed by designated review committees. Reviewers will assign a score on the overall application based on the following review criteria:

Significance

The project addresses cardiometabolic and mental health outcomes involving U.S. Asian adults or comparative research between U.S. Asian adults and other minority populations. The aims of the project advance scientific knowledge, technical capability, and have near-term impact.

Innovation

The application utilizes novel theoretical concepts, approaches or methodologies, instrumentation, or interventions.

Investigator(s)

The PI, collaborators, and other key personnel have the necessary experience and expertise to accomplish the goals of the proposed research project. The investigators have complementary and integrated expertise.

Approach

The overall strategy, methodology, and analyses is well-reasoned and appropriate to accomplish the specific aims of the project.

Career Development

There is a well thought-out and reasonable plan for career development of the junior investigator. Mentor(s) have been identified and the appropriate mechanisms are in place to achieve career development goals outlined.

Potential for External Funding

There is a high likelihood that the proposed research project will lead to NIH or other types of foundation funding.

There are common data elements (CDE) that should be incorporated as much as possible. These will be shared with awardees.

Inquiries regarding our CAHPE and or this funding opportunity should be submitted via email [email protected].

References

  1. Heron M. Deaths: Leading causes for 2017. National Vital Statistics Reports. 2019;68
  2. Holland AT, Wong EC, Lauderdale DS, Palaniappan LP. Spectrum of cardiovascular diseases in Asian-American racial/ethnic subgroups. Annals of epidemiology. 2011;21(8):608-614.
  3. Abesamis CJ, Fruh S, Hall H, Lemley T, Zlomke KR. Cardiovascular Health of Filipinos in the United States: A Review of the Literature. J Transcult Nurs. Sep 2016;27(5):518-28. doi:10.1177/1043659615597040
  4. Gadgil MD, Anderson CA, Kandula NR, Kanaya AM. Dietary patterns in Asian Indians in the United States: an analysis of the metabolic syndrome and atherosclerosis in South Asians Living in America study. J Acad Nutr Diet. Feb 2014;114(2):238-43. doi:10.1016/j.jand.2013.09.021
  5. Mukherjea A, Modayil MV. Culturally specific tobacco use and South Asians in the United States: a review of the literature and promising strategies for intervention. Health Promot Pract. Sep 2013;14(5 Suppl):48S-60S.   doi:10.1177/1524839913485585
  6. Chen M, Hu J. Health disparities in Chinese Americans with hypertension: A review. Int J Nursing Sci. 2014;1:318-322.
  7. Adia AC, Nazareno J, Operario D, Ponce NA. Health Conditions, Outcomes, and Service Access Among Filipino, Vietnamese, Chinese, Japanese, and Korean Adults in California, 2011-2017. Am J Public Health. Apr 2020;110(4):520-526. doi:10.2105/AJPH.2019.305523
  8. Cagney KA, Glass TA, Skarupski KA, Barnes LL, Schwartz BS, Mendes de Leon CF. Neighborhood- level cohesion and disorder: measurement and validation in two older adult urban populations. J Gerontol B Psychol Sci Soc Sci. May 2009;64(3):415-24. doi:10.1093/geronb/gbn041
  9. Cohen S, Kamarck T, Mermelstein R. A global measure of perceived stress. Journal of health and social behavior. 1983:385-396.
  10. Ezzati A, Jiang J, Katz MJ, Sliwinski MJ, Zimmerman ME, Lipton RB. Validation of the Perceived Stress Scale in a community sample of older adults. Int J Geriatr Psychiatry. Jun 2014;29(6):645-52. doi:10.1002/gps.4049
  11. Kim G, Sellbom M, Ford K-L. Race/ethnicity and measurement equivalence of the Everyday Discrimination Scale. Psychological Assessment. 2014;26(3):892.
  12. Marin G, Sabogal F, Marin BV, Otero-Sabogal R, Perez-Stable EJJHJoBS. Development of a short acculturation scale for Hispanics. 1987;9(2):183-205.
  13. Gomez SL, Kelsey JL, Glaser SL, Lee MM, Sidney S. Immigration and acculturation in relation to health and health-related risk factors among specific Asian subgroups in a health maintenance organization. American Journal of Public Health. 2004;94(11):1977-1984.
  14. Wong ST, Yoo GJ, Stewart AL. An empirical evaluation of social support and psychological well-being in older Chinese and Korean immigrants. Ethnicity and Health. 2007;12(1):43-67.
  15. Hale L, Troxel WM, Kravitz HM, Hall MH, Matthews KA. Acculturation and sleep among a multiethnic sample of women: the Study of Women's Health Across the Nation (SWAN). Sleep. 2014;37(2):309-317.
  16. Gao X, Sun F, Hodge DR. Elder mistreatment among Chinese American families: do acculturation and traditionalism matter? The Journals of Gerontology: Series B. 2019;74(3):465-473.
  17. Spitzer RL, Kroenke K, Williams JB. Validity and utility of a self-report version of the PRIME-MD: the PHQ Primary Care Study. Journal of the American Medical Association. 1999 1999;282(18):1737-1744. Not in File.
  18. Lloyd C, Roy T, Begum S, Mughal S, Barnett A. Measuring psychological well‐being in South Asians with diabetes; a qualitative investigation of the PHQ‐9 and the WHO‐5 as potential screening tools for measuring symptoms of depression. Diabetic medicine. 2012;29(1):140-147.
  19. Poongothai S, Pradeepa R, Ganesan A, Mohan V. Reliability and validity of a modified PHQ-9 item inventory (PHQ-12) as a screening instrument for assessing depression in Asian Indians (CURES-65). Journal of the Association of Physicians of India. 2009;57:147-152.
  20. Garabiles MR, Lao CK, Yip P, Chan EW, Mordeno I, Hall BJ. Psychometric validation of PHQ–9 and GAD–7 in Filipino migrant domestic workers in Macao (SAR), China. Journal of personality assessment. 2020;102(6):833-844.
  21. Kroenke K, Spitzer RL, Williams B. The PHQ-9: validty of a new measure for evaluating the severity of somatic symptoms. American Psychomatic Survey. 2002 2002;64(2):258-266. Not in File.
  22. Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. Sep 2001;16(9):606-13. Not in File. doi:10.1046/j.1525-1497.2001.016009606.x
  23. Li C, Friedman B, Conwell Y, Fiscella K. Validity of the Patient Health Questionnaire 2 (PHQ-2) in identifying major depression in older people. J Am Geriatr Soc. Apr 2007;55(4):596-602. Not in File. doi:10.1111/j.1532-5415.2007.01103.x
  24. Pinto-Meza A, Serrano-Blanco A, Penarrubia MT, Blanco E, Haro JM. Assessing depression in primary care with the PHQ-9: can it be carried out over the telephone? Journal of General Internal Medicine. 2055 2055;20(8):738-742. Not in File.
  25. Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of a self-reported measure of medication adherence. Medical care. 1986;24(1):67-74.
  26. Tan X, Patel I, Chang J. Review of the four item Morisky medication adherence scale (MMAS-4) and eight item Morisky medication adherence scale (MMAS-8). INNOVATIONS in pharmacy. 2014;5(3):5.
  27. Morisky DE, Ang A, Krousel‐Wood M, Ward HJ. Predictive validity of a medication adherence measure in an outpatient setting. The journal of clinical hypertension. 2008;10(5):348-354.
  28. Rosenbaum S, Morell R, Abdel-Baki A, et al. Assessing physical activity in people with mental illness: 23-country reliability and validity of the simple physical activity questionnaire (SIMPAQ). BMC psychiatry. 2020;20(1):1-12.
  29. Block G, Gillespie C, Rosenbaum EH, Jenson C. A rapid food screener to assess fat and fruit and vegetable intake. American journal of preventive medicine. 2000;18(4):284-288.
  30. Novotny R, Williams AE, Vinoya AC, Oshiro CE, Vogt TM. US acculturation, food intake, and obesity among Asian-Pacific hotel workers. Journal of the American Dietetic Association. 2009;109(10):1712-1718.
  31. Toobert DJ, Hampson SE, Glasgow RE. The summary of diabetes self-care activities measure: Results from 7 studies and a revised scale. Diabetes Care. 2000;23:943-950.
  32. Association AD. Standards of medical care in diabetes—2010. Diabetes care. 2010;33(Supplement 1):S11-S61.
  33. Whelton           PK,       Carey   RM,      Aronow WS,      et         al.        2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Journal of the American College of Cardiology. 2018;71(19):e127-e248.
  34. Consultation WE. Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet (London, England). 2004;363(9403):157-163.

 

Published:
11/17/2022